What is Isopropylmagnesium bromide solution for Chemical Raw Materials CAS 920-39-8 ?
Isopropylmagnesium Bromide (CAS 920-39-8) is an organomagnesium compound also known as bromo(isopropyl)magnesium and magnesium, bromo(1-methylethyl)-. With a molecular formula of C₃H₇BrMg and a molecular weight of 147.3, it belongs to the alkyl Grignard reagent class. This compound typically exists as a dark gray to dark brown transparent solution in solvents like tetrahydrofuran (THF) or 2-methyltetrahydrofuran (2-MeTHF).
Isopropylmagnesium Bromide has a density of 0.982 g/mL (25 degree , THF solution), a flash point of -17 degree , and melting point of 114–116 degree (pure form). It is soluble in aprotic solvents such as THF and diethyl ether but insoluble in hydrocarbons. Contact with water or alcohol triggers violent reactions, releasing flammable gases (e.g., propane) and forming magnesium hydroxide.
Isopropylmagnesium bromide solution for Chemical Raw Materials CAS 920-39-8
| 920-39-8 | |
| 213-056-8 | |
| C3H7BrMg | |
| 147.3 | |
Carbonyl Addition: Reacts with aldehydes, ketones, and esters to generate isopropyl alcohols (e.g., forming 2,3-dimethyl-2-butanol with acetone).
Metal-Catalyzed Coupling: Undergoes palladium/nickel-catalyzed cross-coupling with halogenated hydrocarbons to introduce isopropyl groups, supporting the synthesis of drug intermediates or complex hydrocarbons.
It is flammable when wet (H260), highly corrosive (H314), and can cause skin burns and eye damage.
Vapor irritates the respiratory tract (H335), and is harmful if inhaled or ingested (H302/H332).
Storage conditions: Store in a cool and dry place after sealing, away from oxidants and acidic substances, and avoid long-term exposure to air.
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